Literaturhinweise


Comparison Of In Vivo Red Cell Survival Of Donations Collected By Haemonetics MCS Versus Conventional Collection

Regan, F.; Teesdale, P.; Garner, S.; Callaghan, T.; Brennan, M.; Contreras, M. North London Blood Transfusion Centre, Colindale, London, U.K. Transfusion Medicine, 1997, 7, 25 - 28

Article showing no detrimental effect on in vivo survival of red cells of apheresis processing compared to manual processing.


Red Cell Collection By Apheresis Technology
Meyer, D.; Bolgiano, D. C.; Syaers, M.; Price, R.; Benson, D.; Slichter, S. J. Puget Sound Blood Centre And The Department Of Medicine, University Of Washington School Of Medicine, Seattle, Washington. Transfusion - Vol. 33, No. 10 - 1993

To determine the feasibility of collecting 2 units (450 ml) of red cells per donation by apheresis technology, apheresis red cell collections were compared to whole-blood donations.


Effect On Cardiovascular Function And Iron Metabolism Of The Acute Removal Of Two Units Of Red Cells
Sherman, L. A.; Lippmann, M. B.; Ahmed, P.; Buchholz, D. H. American Red Cross Blood Services, Jewish Hospital Of St.Louis and Washington University, St. Louis. Transfusion - Vol. 34, No. 7 - 1994

The collection of a donor of 2 red cell units at one time would decrease recipient exposure to viruses and alloantigens. If the donor is a large person, the blood volume lost and the postdonation hemoglobin and/or hematocrit should be within acceptable limits.


A Randomized, Double Blind Comparison Of Donor Tolerance Of Sham, 400 ml, 200 ml, and Sham Red Cell Donation
Smith, KJ.; James, Ds.; Hunt, WC.; McDonough, W.; Quintana, R. Departments Of Pathology, Medicine and Epidemiology and Cancer Control, University Of New Mexico, School Of Medicine, New Mexico. Transfusion - Vol. 36, No. 8 - 1996

Donor tolerance of red cell donations of 414 +/- 21 ml, a volume of red cells twice that in a standard 450 ml blood donation, does not differ from donor tolerance of standard or sham donations. Physiologic adjustments and hematopoietic response to reduced red cell mass were greater in the 2 unit group, but the donation of 1 unit or 2 units did not cause detectable symptoms of reduced oxygen-carrying capacity.


Automated Blood Component Collection With The MCS 3p Cell Separator:
Evaluation Of Three Protocols For Buffy Coat-Poor And White Cell-Reduced Packed Red Cells And Plasma Zeiler, T. A.; Kretschmer, V. Department Of Transfusion Medicine And Hemostaseology, Philipps-University, Marburg, Germany. Transfusion - 1997; 37; 791 - 97

Erythroplasmapheresis with 3 protocols (DRBCP, RBCPF and DRBCPF) was performed without technical problems. The biochemical parameters of the RBCs (until day 49) were as good or even better as with standard preparations from whole blood donation.


Red Cell Apheresis: New Concepts Of Blood Component Processing
Matthes, G. A. Institute Of Transfusion Medicine, Centre for Blood And Cancer Diseases Berlin, Berlin. Official Jounal of the International Society for Aphersis and the Japanese Society for Apheresis, Vol. 1; 1; 2/1997

All collected blood components fit the standards of European guidelines. The results for red cell concentrate storage are as good as the results for manual collection or better. Storage data of platelets concentrates are similar to platelet apheresis. All apheresed blood products are sterile after storage. Red cell apheresis procedures are a challenge for blood component processing and will encourage a revision of the national blood and plasma programs for self-sufficiency.


Two-Unit Red Cell Apheresis And Its Potential Advantages Over Traditional Whole-Blood Donations
Shi, P. A.; Ness, P. M. Transfusion Medicine Division, Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland. Transfusion - Vol. 39; 1999; 218 - 225

Apheresis RBC units contain a defined amount of RBCs per unit, rather than the variable amount in whole-blood units. The RBC apheresis saves money by decreasing the amount of component processing, technical preparation time, quality control, paperwork and testing (to one set of laboratory tests/2 units).